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This report provides information on potential drug interactions between two medications:

If you are taking both of these drugs, it is important to talk to your doctor before continuing. Combining them can increase the risk of side effects and a rare but serious condition called serotonin syndrome. Symptoms of serotonin syndrome include confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. If you experience any of these symptoms while taking these medications, contact your doctor immediately. It is also important to inform your doctor of all other medications you are taking, including vitamins and herbs. Do not stop taking any medication without consulting your doctor.

Additionally, using phentermine with alcohol can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. You may also be more likely to experience nervous system side effects such as dizziness, drowsiness, depression, and difficulty concentrating. Avoid or limit the use of alcohol while taking phentermine. Do not exceed the recommended dose of phentermine and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you.

Duloxetine may cause liver damage, and taking it with alcohol may increase that risk. Avoid or limit the use of alcohol while being treated with duloxetine. Contact your doctor immediately if you experience fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, dark colored urine, or yellowing of the skin or the whites of your eyes, as these may be symptoms of liver damage. Inform your doctor of all other medications you are taking, including vitamins and herbs. Do not stop taking any medication without consulting your doctor.

No therapeutic duplication warnings were found for these medications. However, it is always important to consult with your healthcare provider before starting or stopping any medication.

Drug Interaction Classification

The following classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer: This article is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions you may have regarding a medical condition.

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